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TriLink Launches Analytical Sciences Center of Excellence

4,000-sq.-ft. lab to support drug developers from plasmid DNA to mRNA manufacturing and release.

By: Anthony Vecchione

TriLink BioTechnologies, a Maravai LifeSciences company and global provider of life science reagents and services, has launched its Analytical Sciences Center of Excellence (ASCE) hub, expanding its suite of analytical testing capabilities. The new CoE aims to minimize the delays and unexpected costs typically associated with outsourced testing to multiple labs and will serve as the hub for all analytical innovation and the Quality Control labs across the company’s manufacturing network.

Located within Maravai LifeSciences’s Pacific Center Boulevard facility in San Diego’s Sorrento Valley, the ASCE will operate out of a 4,000-sq.-ft. lab equipped with advanced instrumentation to support drug developers starting with plasmid DNA and continuing through mRNA manufacturing and release.

TriLink has developed and qualified 10 types of unique methods for the characterization of mRNA covering 40 various constructs. With this expansion, the CoE builds on method development for construct-specific assays with new instrumentation to improve NMR, NGS, and LNP characterization. The center of excellence also aims to develop cutting-edge analytical methodologies, including mRNA fingerprinting and sequencing.

Kevin Lynch, TriLink’s vice president and general manager of GMP Operations said, “We continue to witness exciting growth in nucleic acid therapeutics – and rapid expansion calls for rapid innovation. The ASCE’s centralized analytical capabilities and development of analytical methodologies for the characterization of nucleic acids will advance the industry as we continue to find ways to meet the needs of developers working on life-saving therapeutics.”

In addition to the ASCE’s suite of analytical services, TriLink has an mRNA capping portfolio, advanced scale-up capabilities, and expertise in mRNA, oligonucleotide, and plasmid production.

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